Colorectal Cancer Genetics
All colorectal cancers induced by a heritable mutation – a genetic change that can be passed on from parent to child. The major subtypes of hereditary colon cancer and some rare conditions include an inherited risk for colorectal cancer. In some families if there is a strong hint or symptoms present genetically from ancestors, may pass that mutated gene from parent to offspring. The disease susceptibility of these families occurs randomly or by hereditary mutations which might not been observed that easily because mutation occurs in gene like APC, KRAS, TP53, SMAD4 which leads to grow cell uncontrollably resulting in Colorectal Cancer.Genetic counselors and physicians can help understand colorectal cancer risk and type based on it.